Clinical reviews
White Papers
Each paper is a structured clinical review at peer-review depth. Primary citations. Honesty Scale ratings on every claim. Authored and reviewed by Dr. Job Mogire, MD, FACP, FACC.
- 01The Hundred-Dollar Look at Your Death
A clinical review of the coronary artery calcium score: what it measures, what the evidence supports, and what your result means.
Includes: CAC Score Conversation Guide
- 01The Heart Attack and the Ischemia That the Angiogram Cannot See
A clinical review of MINOCA and INOCA: ischemic heart disease without obstructive coronary disease, disproportionately affecting women
Includes: MINOCA / INOCA Workup Checklist
- 02The Number Your Doctor Didn't Order
ApoB is a more accurate measure of cardiovascular risk than LDL. It is not on your standard panel. This paper explains why it matters.
Includes: ApoB Lab Order Template
- 02Small-Vessel Disease: When the Problem Is in Arteries the Angiogram Cannot Resolve
A clinical review of coronary microvascular dysfunction: the pathophysiology, how it is diagnosed through coronary function testing
Includes: Coronary Function Testing Explainer
- 03The Penile Artery Is the Canary in the Coronary
Erectile dysfunction of vascular origin is a cardiovascular event. This paper reviews the evidence connecting penile and coronary arterial health.
Includes: Vascular Risk Conversation Guide
- 03Spontaneous Coronary Artery Dissection: The Heart Attack That Is Not Atherosclerosis
A clinical review of spontaneous coronary artery dissection (SCAD): a non-atherosclerotic heart attack predominantly in women
Includes: SCAD Patient Resource Guide
- 04Your Snoring Is Killing You. A Clinical Review of Sleep Apnea in High-Functioning Men.
Obstructive sleep apnea carries cardiovascular risk equivalent to hypertension. This paper reviews the mechanism and what to do about it.
Includes: Sleep Apnea Conversation Script
- 04Takotsubo Cardiomyopathy: The Broken-Heart Syndrome Is a Real Diagnosis
A clinical review of Takotsubo (stress) cardiomyopathy: a transient heart failure syndrome that mimics heart attack, predominantly in postmenopausal women.
Includes: Takotsubo Recovery Guide
- 05Why You're Tired, Soft, and Empty at 47
A clinical review of the cortisol-testosterone seesaw: how chronic stress suppresses testosterone and what the cardiovascular consequences are.
Includes: Cortisol-Testosterone Lab Guide
- 05Preeclampsia as a Cardiovascular Diagnosis: A Pregnancy Complication That Forecasts the Heart
A clinical review of preeclampsia as a long-term cardiovascular risk factor: the magnitude of risk, the mechanisms
Includes: Post-Preeclampsia Heart Plan
- 06What Your Whoop Score Is Not Telling You About Your Heart
HRV is the most clinically interesting wearable metric and the most oversold. A cardiologist reviews the evidence and what the 90-day trend means.
Includes: HRV Honest Interpretation Guide
- 06The Menopause Transition as a Cardiovascular Inflection Point
A clinical review of the menopause transition and cardiovascular risk: the documented shifts in lipids, vasculature, and body composition
Includes: Menopause Heart Plan
- 07The Social Cause of My Patients' Heart Attacks
Social isolation carries cardiovascular mortality risk comparable to smoking. A cardiologist reviews the mechanism and the clinical implications.
Includes: Connection Risk Assessment Guide
- 07The Reproductive Risk Stack: How a Woman's History Accumulates Into Cardiovascular Risk
A clinical review of reproductive risk enhancers, from preeclampsia to early menopause and PCOS, accumulating across a woman's life into elevated cardiac risk.
Includes: Reproductive History Risk Worksheet
- 081 in 63 Before 45. The Black Man's Cardiovascular Inheritance.
One in 63 Black men dies of cardiac causes before 45. A Kenyan-born board-certified cardiologist reviews the data and what changes it.
Includes: Cardiovascular Risk Conversation Guide for Black Men
- 08The Yentl Phenomenon: How the Evidence Base Built on Men Still Costs Women
A clinical review of the Yentl phenomenon and the dismissal gap: how a male-derived evidence base and atypical-symptom framing contribute to missed diagnoses
Includes: Advocacy Script for the Cardiology Visit
- 09The Heart Disease No One Is Diagnosing
Alexithymia doubles all-cause mortality in middle-aged men. A cardiologist reviews the evidence and why it is absent from clinical practice.
Includes: Emotional Awareness and Cardiovascular Risk Assessment
- 09Autoimmune Atherosclerosis: How Chronic Inflammation Accelerates Heart Disease in Women
A clinical review of accelerated atherosclerosis in autoimmune disease: the inflammatory mechanism, the earlier cardiovascular risk in conditions like lupus
Includes: Autoimmune Heart-Risk Checklist
- 10Cardio-Oncology in Women: Protecting the Heart Through Cancer Treatment
A clinical review of cardio-oncology in women: how anthracyclines, HER2-targeted therapy, and chest radiation can affect the heart
Includes: Survivorship Heart-Health Guide
- 10The Test Your Annual Physical Doesn't Order (But Should)
Fasting insulin identifies insulin resistance years before glucose rises. A cardiologist reviews the evidence, the mechanism, and the clinical gap.
Includes: Metabolic Risk Lab Guide
- 11The Drug That Surprised Cardiologists. GLP-1 Receptor Agonists and the Heart.
The SELECT trial showed semaglutide reduced cardiovascular death, heart attack, and stroke by 20 percent in non-diabetic cardiac patients.
Includes: GLP-1 Cardiovascular Safety Guide for Men With Established Heart Disease
- 11Sex-Specific Lipids: Reading a Woman's Cholesterol With the Right Tools
A clinical review of lipids in women: the menopause-related shift in LDL and ApoB, why ApoB and Lp(a) sharpen risk
Includes: Lipid Panel Decoder for Women
- 12The Held-Load Sequence: A Clinical Model of How Women's Hearts Are Lost
The clinical model linking sustained load, stress physiology, and non-obstructive cardiac disease as the dominant pathway for how women's hearts are lost.
Includes: The Held-Load Sequence: Where Are You on the Chain?
- 12Inflammation's Invoice. What Your hs-CRP Is Actually Telling Your Cardiologist.
hs-CRP above 3 mg/L doubles cardiovascular mortality independent of LDL. JUPITER showed 44 percent MACE reduction with statin therapy in high-CRP patients.
Includes: hs-CRP Interpretation and Action Guide
- 13Autonomic Sovereignty. A Cardiologist's Audit of How High-Achieving Men Lose, and Reclaim, Control of Their Own Nervous System.
Chronic sympathetic overdrive in men 35 to 55 is a cardiovascular event in slow motion. A cardiologist audits cold exposure, sauna, HRV devices
Includes: The Autonomic Sovereignty Self-Audit for Men 35 to 55
- 14The Qualifying Event: Why Prevention Cardiology Is Reimbursement-Asymmetric and How That Asymmetry Kills Patients
A cardiologist examines why the US healthcare system pays more for heart attack treatment than prevention, what the reimbursement asymmetry costs patients